Je me posais une question depuis un petit bout de temps:
« Est-ce que le fait d’être menstrue nous avantageait par rapport aux hommes CADASILIENS? »
Pourquoi cette interrogation? Parce que les sœurs de mon père et ses frères ont commencé à se faire des partys d’AVC plus âgées que ceux-ci.
Sur le net, je suis tombée sur ceci, c’est bien sûr en anglais :
In the general population, migraine, cerebrovascular diseases, and vascular dementia differ in many aspects between men and women. CADASIL is considered a unique model to investigate migraine with aura, stroke, and dementia related to ischemic small vessel disease. This study aims to evaluate the effect of gender on the main clinical and neuroimaging characteristics of CADASIL. Cross-sectional data from 313 CADASIL patients including various clinical and cognitive scores and MRI parameters were compared between men and women, and between those younger and older than the median age of the population corresponding to the usual age of menopause (51 years). At younger than 51 years, migraine with aura was 50% more prevalent in women and stroke was 75% more prevalent in men. After the fifth decade, men had higher National Institutes of Health Stroke Scale and Rankin scores than women and more severe executive dysfunction, although global cognitive scores were similar. Age at first stroke, the number of stroke events, and the prevalence of dementia and psychiatric symptoms did not differ between men and women. Brain volume was lower in men with a trend for a larger volume of lacunar infarcts. In CADASIL, migraine with aura is more frequent in women and stroke is more frequent in men before the age of menopause. This difference seems to vanish after this age limit but may result in a higher degree of cognitive impairment and cerebral atrophy in men at the late stage of the disease. The presumable role of ovarian hormones in these gender-related differences remains to be explored.
TY - JOUR
AU - Gunda, Bence
AU - Herve, Dominique
AU - Godin, Ophélia
AU - Bruno, Martina
AU - Reyes, Sonia
AU - Alili, Nassira
AU - Opherk, Christian
AU - Jouvent, Eric
AU - Duering, Marco
AU - Bousser, Marie-Germaine
AU - Dichgans, Martin
AU - Chabriat, Hugues
PY - 2012/01/01
SP - 137
EP - 41
VL - 43
DO - 10.1161/STROKEAHA.111.631028
JO - Stroke; a journal of cerebral circulation
ER -
Conclusion de tout ça: femmes CADASILIENNES encore en menstrues, soyons heureuses et ne ménopausons pas avant la fin cinquantaine minimum! 😅🤣😇
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